Ro 11-1464 induces the hepatic  of apoA-1 and leads to increased levels of apoA-1 in the plasma.

HMG-CoA reductase and acetyl-CoA carboxylase inhibitor.

Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor.

SR1848 is a cell penetrant and potent inhibitor of orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) that reduces the  of CyclinD1 and E1, which results in inhibition of cell proliferation.

TFCA is a Liver X receptor α (LXRα) antagonist that reduces lipid accumulation and fatty liver in mice.

Triacsin C is a potent inhibitor of long-chain fatty acyl CoA synthetase.

Inhibitor of cholesterol synthesis (inhibits desmosterol Δ24-reductase).

Potent inhibitor, in vivo and in vitro, of mammalian, fungal and Saccharomyces cervisiaesqualene synthase.