l General Information |
Product Name | Ro 11-1464 |
General description | Ro 11-1464 induces the hepatic of apoA-1 and leads to increased levels of apoA-1 in the plasma. |
Synonym | 9-Methyl-4-phenyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine |
Purity | ≥98.0%(HPLC) | CAS Number | 54123-09-0 |
Formula | C15H12N4S | Molecular Weight | 280.35 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to beige Solid |
Solubility(25℃) | DMSO | ≥5mg/mL |
l Biological Information |
Biochem/Physiol Actions | Ro 11-1464 induces the hepatic of apoA-1 and leads to increased levels of apoA-1 in the plasma. Treatment of human apoA-1 transgenic mice with Ro 11-1464 resulted in a three-fold increase in hapoA-1 mRNA in the liver, and a two-fold increase in plama apoA-1levels. The compound causes a significant decrease in plama lipids and enhances reverse cholesterol transport. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
