Arachidonic acid is an unsaturated ω6 fatty acid constituent of the phospholipids of cell membranes.

Clonixin is a non steroidal anti inflammatory drug (NSAID) with analgesic properties.

SC-560 is selective cyclooxygenase-1 (COX-1) inhibitor, exhibiting 700-fold selectivity for COX-1 over COX-2.

Tenidap is an anti-inflammatory and anti-rheumatic with a variety of activities. Tenidap preferentially inhibits COX-1 with an IC50 value of 30 nM, and also has some lesser inhibitory activity towards COX-2 and 5-lipoxygenase (IC50 values are 1.2 and > 30 μM for COX-2 and 5-lipoxygenase respectively). Tenidap is also a cytokine modulator, an opener of inward rectifying hKIR2.3 channels (EC50 = 402 nM) and has been shown to modulate cytoplasmic pH and inhibit anion transport in vitro.

Tryptanthrin is a plant alkaloid with anti-inflammatory and anti cancer activities.

Timnodonic acid is a 5-Lipoxygenase inhibitor

PF-03549184 (PF-9184) is a potent inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1).

Arachidonic acid metabolite via cytochrome P4504A that is an activator of the Ras/MAP pathway.