Podophyllotoxin is a potent spindle poison, toxic if taken internally, and has been used as a cathartic.

Ofloxacin is a synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Fidaxomicin is a narrow-spectrum, 18-membered macrolide antibiotic isolated from the actinomycete Dactylosporangium aurantiacum subsp. hamdenensis with potential antibacterial activity.

Streptozocin is an antibiotic that is produced by Stretomyces achromogenes.

Mirin is a potent Mre11–Rad50–Nbs1 (MRN) complex inhibitor, and inhibits Mre11-associated exonuclease activity.

BGP-15 dihydrochloride is a nicotinic amidoxime derivative with PARP inhibitory activity.

SCR7 is a specific DNA Ligase IV inhibitor.

VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki of 13 nM and IC50 of 26 nM in cell-free assay.