l General Information |
Product Name | Ofloxacin |
General description | Ofloxacin is a synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. |
Synonym | (RS)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid; Ofloxacine; Floxin |
Purity | ≥99.0%(HPLC) | CAS Number | 82419-36-1 |
Formula | C18H20FN3O4 | Molecular Weight | 361.37 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Pale yellow or bright yellow |
Solubility(25℃) | DMSO | Slightly soluble |
Ethanol | Very slightly soluble |
Water | Slightly soluble |
l Biological Information |
Biochem/Physiol Actions | Ofloxacin is a fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting in cell death in sensitive bacterial species. |
Application | 1. Anti-Bacterial Agents 2. Anti-Infective Agents, Urinary 3. Cytochrome P-450 CYP1A2 Inhibitors 4. Topoisomerase II Inhibitors |
l Packaging & Storage |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
