Primary prostaglandin in brain; induces inflammation; stimulates adenylyl cyclase.

K-604 inhibits against acyl-coenzyme A (acyl-CoA):cholesterol O-acyltransferase-1 (ACAT1, SOAT1) activitiy in a selective (IC50 = 450 nM vs. 102.85 μ M against human ACAT1 and ACAT2, respectively) and acyl-CoA-competitive (Ki = 378 nM against oleoyl-coA) manner.

BMS-303141 is a potent inhibitor of ATP citrate lyase (ACL).

Accumulated macrophages in atherosclerotic plaques result in plaque rupture and thrombus formation.

≥98% (TLC)

CP-532623 is a potent inhbitor of cholesteryl ester transfer protein (CETP) that leads to elevated high-density lipoprotein cholesterol levels.

Lanosterol is a tetracyclic triterpenoid and is the compound from which all animal and fungal steroids are derived.

PF-05175157 is a potent and selective inhibitor of both acetyl-CoA carboxylase isoform ACC1 located primarily in liver and adipose tissue and isoform ACC2 dominant in skeletal and heart muscle, with IC50 values of 27 nM and 33 nM, respectively.