Rufinamide is a voltage-gated sodium channel blocker, used an anticonvulsant medication.

Ivermectin is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug.

Omeprazole is a proton pump inhibitor, used to treat dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, laryngopharyngeal reflux, and Zollinger–Ellison syndrome.

Zosuquidar (LY335979) 3HCl is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of 60 nM in a cell-free assay.

Prilocaine is a local anesthetic of the amino amide type. It acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation.

Dofetilide is a selective potassium channel ((hERG)) blocker, used as a Class III antiarrhythmic drug.

Isradipine is a potent and selective L-type voltage-gated calcium channel blocker, used to treat high blood pressure.

Lubiprostone is an activator of ClC-2 chloride channels, used in the management of idiopathic chronic constipation.