l General Information |
Product Name | Prilocaine |
General description | Prilocaine is a local anesthetic of the amino amide type. It acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. |
Synonym | NSC 40027; N-(2-methylphenyl)-2-(propylamino)propanamide |
Purity | ≥98.0%(HPLC) | CAS Number | 721-50-6 |
Formula | C13H20N2O | Molecular Weight | 220.316 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥35mg/ml |
Ethanol | ≥35mg/ml |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol
Actions | Prilocaine is a toluidine derivative and intermediate-acting amino amide with local anesthetic property. Prilocaine stabilizes the neuronal membrane by preferential binding to and inhibiting depolarization of the voltage-gated sodium channel. This results in a decrease in membrane permeability and subsequent inhibition of the ionic sodium influx required for the initiation and conduction of impulses. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
