Pirfenidone is an orally active synthetic antifibrotic agent structurally similar to pyridine 2,4-dicarboxylate.

SIS3 hydrochloride is a novel specific inhibitor of Smad3.

ITD-1 is a potent and highly selective TGFβ pathway inhibitor.

LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor.

SB431542 is a potent and selective inhibitor of ALK5.

LDN-193189 is a selective BMP signaling inhibitor.

Galunisertib is a potent TGFβ receptor I (TβRI) inhibitor.

SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5).