GW788388 is a potent and selective inhibitor of ALK5.

LY364947 is a potent ATP-competitive inhibitor of TGFβR-I.

RepSox is a potent and selective inhibitor of the TGFβR-1/ALK5.

Kartogenin is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.

Vactosertib is a highly potent, selective, and orally bioavailable TGF-β receptor ALK4/ALK5 inhibitor.

DMH1 is a selective BMP receptor inhibitor.

SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5 with IC50 of 129 nM and 47 nM in cell-free assays, respectively, also inhibits ALK7, but does not inhibit ALK1, 2, 3, or 6.

Sotrastaurin is a potent and selective pan-PKC inhibitor, mostly for PKCθ with Ki of 0.22 nM in a cell-free assay inactive to PKCζ.