Ipatasertib is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity.
Capivasertib is an orally available inhibitor of the serine/threonine protein kinase AKT (protein kinase B) with potential antineoplastic activity.
AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA.
TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics.
CHIR-99021 HCl is a GSK-3α/β inhibitor.
SB216763 is a potent and selective GSK-3 inhibitor.
TWS119 is a GSK-3β inhibitor.
Tideglusib is an irreversible, non ATP-competitive GSK-3β inhibitor.