l  General Information  | 
Product Name  | TIC10  | 
General description  | TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics.  | 
Synonym  | ONC201  | 
Purity  | ≥98.0%(HPLC)  | CAS Number  | 1616632-77-9  | 
Formula  | C24H26N4O  | Molecular Weight  | 386.49  | 
Suitability  | BioReagent, suitable for cell culture, etc.  | 
l  Physical and Chemical Information  | 
Appearance  | solid  | 
Solubility(25℃)  | DMSO  | ≥50mg/mL(warmed)  | 
Ethanol  | ≥50mg/mL(warmed)  | 
Water  | Insoluble  | 
l  Biological Information  | 
Biochem/Physiol
  Actions  | TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics.  | 
l  Storage  | 
Storage temp.  | -20℃  | 
l  Precautions and Disclaimer  | 
This
  product is for R&D use only, not for drug, household, or other uses.  | 
l  References  | 
1.    http://www.drugbank.ca 2.    https://ncit.nci.nih.gov 3.    https://www.ncbi.nlm.nih.gov  |