Apitolisib is a potent, class I PI3K inhibitor for PI3Kα/β/δ/γ.

Duvelisib is a novel and selective PI3K δ/γ inhibitor.

Gedatolisib is a highly potent dual inhibitor of PI3Kα, PI3Kγ and mTOR.

Fimepinostat is a dual PI3K and HDAC inhibitor for PI3Kα and HDAC1/2/3/10.

Copanlisib (BAY 80-6946) is a potent pan-class I PI3K with IC50 of 0.5, 3.7, 6.4, and 0.7 nM in cell-free assays for PI3Kα/β/γ/δ , respectively.

VPS34 inhibitor 1 (PIK-III analogue) is a potent and selective inhibitor of VPS34 with an IC50 of 15 nM.

AZD8055 is a novel ATP-competitive mTOR inhibitor .

Temsirolimus is a specific mTOR inhibitor.