CYM50179 is a potent, selective agonist of the sphingosine-1-phosphate receptor 4 (S1P4).

CYM50358 is a potent, selective antagonist of the sphingosine-1-phosphate receptor 4 (S1P4).

CYM-5442 is a highly-selective S1P1 (Spingosine 1-Phosphate Receptor 1) agonist

CYM-5520 is a specific, noncompetitive allosteric agonist of sphingosine 1-phosphate receptor 2 (S1PR2; EC50 = 1.0 μM).

CYM-5541 is an allosteric agonist selective for the Sphingosine 1-phosphate (S1P) S1P3 receptor subtype.

Novel, selective human sphingosine-1-phosphate subtype 1 (S1P1) receptor agonist.

Potent S1P(1) competitive antagonist

Rimonabant is an inverse agonist for the cannabinoid receptor CB1. Its main avenue of effect is reduction in appetite.