Product Name

W146 hydrate

General description

Potent S1P(1) competitive antagonist

Synonym

ML056; R-3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid hydrate, [(3R)-3-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic  acid

Purity

≥98.0%(HPLC)

CAS Number

909725-61-7 (anhydrous)

Formula

C¹⁶H²⁷N²O⁴P · xH²O

Molecular Weight

342.37 (anhydrous basis)

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Off-white Solid

l  Biological Information

Biochem/Physiol  Actions

Potent S1P(1) competitive antagonist; Ki = 10-77 nM.

Application

W146 hydrate has been used to assess vascular permeability in mice

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov