l General Information |
Product Name | SEW2871 |
General description | Novel, selective human sphingosine-1-phosphate subtype 1 (S1P1) receptor agonist. |
Synonym | 5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]- 1,2,4-oxadiazole |
Purity | ≥98.0%(HPLC) | CAS Number | 256414-75-2 |
Formula | C20H10F6N2OS | Molecular Weight | 440.36 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White Solid |
Solubility(25℃) | DMSO | ≥10mg/mL |
Water | insoluble |
l Biological Information |
Biochem/Physiol
Actions | Novel, selective human sphingosine-1-phosphate subtype 1 (S1P1) receptor agonist. SEW2871 is a selective agonist of spingosine-1 phosphate receptor. It exacerbates reperfusion arrhythmias by significantly prolonging the duration of ventricular tachycardia and ventricular fibrillation.SEW2871 modulates inflammatory reactions by influencing lymphocyte homing and cell migration.By the inhibition of proinflammatory molecules, SEW2871 reduces acute renal failure due to ischemia. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
