Azacitidine is a nucleoside analogue of cytidine that specifically inhibits DNA methylation by trapping DNA methyltransferases.

RG108 is an inhibitor of DNA methyltransferase.

Pinometostat is an S-adenosyl methionine (SAM) competitive inhibitor of protein methyltransferase DOT1L.

EPZ005687 is a potent and selective inhibitor of EZH2.

GSK343 is a potent and selective EZH2 inhibitor.

Tazemetostat (EPZ-6438) is a potent, and selective EZH2 inhibitor.

NC1999 is a potent, orally bioavailable and selective inhibitor of EZH2 and EZH1.

EPZ015666 is a potent, selective and orally bioavailable PRMT5 inhibitor.