l General Information |
Product Name | Tryptanthrin |
General description | Tryptanthrin is a plant alkaloid with anti-inflammatory and anti cancer activities. |
Synonym | NSC 349447, Tryptanthrine; Couroupitine A, Indolo(2,1-b)quinazoline-6,12-dione |
Purity | ≥98.0%(HPLC) | CAS Number | 13220-57-0 |
Formula | C15H8N2O2 | Molecular Weight | 248.24 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Faintly Yellow to Dark Yellow Solid |
Solubility(25℃) | DMSO | ~2 mg/mL (warmed) |
l Biological Information |
Biochem/Physiol Actions | Tryptanthrin is a plant alkaloid with anti-inflammatory and anti cancer activities. Tryptanthrin blocks leukotriene production in neutrophils and in whole blood assays, and in an in vivo rat pleurisy model. The compound also inhibits P-glycoprotein, and sensitizes resistant cancer cell lines to killing by cytotoxic agents. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
