Nanocarrier CCG-222740 significantly decreased ACTA2 gene and was not cytotoxic in human conjunctival fibroblasts.
Theophylline is a nive phosphodiesterase (PDE) inhibitor, adenosine receptor blocker, and histone deacetylase (HDAC) activator.
BI-3406 is a potent, orally active and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with IC50 of 6 nM. BI-3406 reduces the formation of GTP-loaded KRAS, and inhibits MAPK pathway signaling with anticancer activities.
JNK-IN-8 is the first irreversible JNK inhibitor for JNK1, JNK2 and JNK3.
Anisomycin is an antibiotic, which inhibits protein synthesis, and also act as a JNK activator.
Tanespimycin is a benzoquinone antineoplastic antibiotic derived from the antineoplastic antibiotic geldanamycin.
Luminespib is a highly potent HSP90 inhibitor for HSP90α/β.
Alvespimycin Hydrochloride is the hydrochloride salt of alvespimycin, an analogue of the antineoplastic benzoquinone antibiotic geldanamycin.