Product Name

Anisomycin

General description

Anisomycin is an antibiotic, which inhibits protein synthesis, and also act as a JNK activator.

Synonym

[(2R,3S,4S)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl]  acetate; Flagecidin 

Purity

≥98.0%(HPLC)

CAS Number

22862-76-6

Formula

C¹⁴H¹⁹NO⁴

Molecular Weight

265.3

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25℃)

DMSO

≥40mg/mL(warmed)

Ethanol

≥15mg/mL(warmed)

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

Anisomycin is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. It has a role as an antiparasitic agent, a DNA synthesis inhibitor, a protein synthesis inhibitor, an antineoplastic agent, an antimicrobial agent and a bacterial metabolite. It is a monohydroxypyrrolidine and an organonitrogen heterocyclic antibiotic.

Anisomycin is an antibiotic, which inhibits protein synthesis, and also act as a JNK activator.

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov