l General Information |
Product Name | CCG-222740 |
General description | Nanocarrier CCG-222740 significantly decreased ACTA2 gene and was not cytotoxic in human conjunctival fibroblasts. |
Purity | ≥98.0%(HPLC) | CAS Number | 1922098-69-8 |
Formula | C23H19ClF2N2O3 | Molecular Weight | 444.865 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Off-white or beige powder |
Solubility(25°C) | DMSO | ≥25mg/mL |
Ethanol | ≥25mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol
Actions | CCG-222740 is a potent and selective Rho/myocardin-related transcription factor (MRTF) pathway inhibitor.CCG-222740 also is a potent inhibitor of alpha-smooth muscle actin protein. CCG-222740 effectively reduces fibrosis in skin and blocks melanoma metastasis. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not
for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
