COH29 is an orally available, aromatically substituted thiazole and inhibitor of the human ribonucleotide reductase (RNR), with potential antineoplastic activity.
Palbociclib HCl is a highly selective inhibitor.
Seliciclib is an orally available small molecule and CDK inhibitor with potential apoptotic and antineoplastic activity.
SNS-032 has firstly been described as a selective inhibitor of CDK2.
AZD5438 is a potent inhibitor of CDK1/2/9.
MK-8776 (SCH 900776) is a selective Chk1 inhibitor with IC50 of 3 nM in a cell-free assay. It shows 500-fold selectivity against Chk2.
Palbociclib Isethionate is the isethionate salt form of palbociclib, an orally available CDK inhibitor with potential antineoplastic activity.
Abemaciclib mesylate is a potent and selective inhibitor of CDK4 and CDK6.