Palbociclib (PD-0332991) HCl
Product #：
TS0320
Image
SKU-Pack Size
Stock
Price($)
Quantity
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TS0320-5MG
In-stock
94
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+
TS0320-10MG
In-stock
120.4
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TS0320-50MG
In-stock
336
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+
Details
l General Information |
Product Name | Palbociclib (PD-0332991) HCl |
General description | Palbociclib HCl is a highly selective inhibitor. |
Synonym | 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one; hydrochloride |
Purity | ≥98.0%(HPLC) | CAS Number | 827022-32-2 |
Formula | C24H29N7O2·HCl | Molecular Weight | 483.99 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25℃) | DMSO | ~3mg/mL(warmed) |
Ethanol | Insoluble |
Water | ≥25mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Palbociclib HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays, respectively. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. |
l Storage |
Storage
temp. | -20℃ |
l Precautions and Disclaimer |
This
product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
