Abemaciclib (LY2835219) mesylate
Product #:
TS0326
Image
SKU-Pack Size
Stock
Price($)
Quantity
-
-
TS0326-5MG
In-stock
130
-
+
TS0326-10MG
In-stock
200
-
+
TS0326-25MG
In-stock
358
-
+
Details
l General Information |
Product Name | Abemaciclib mesylate |
General description | Abemaciclib mesylate is a potent and selective inhibitor of CDK4 and CDK6. |
Synonym | N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine; methanesulfonic acid; LY2835219 mesylate |
Purity | ≥98.0%(HPLC) | CAS Number | 1231930-82-7 |
Formula | C27H32F2N8·CH4O3S | Molecular Weight | 602.7 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ≥20mg/mL |
Water | ≥50mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Abemaciclib mesylate is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |