XAV-939 selectively inhibits Wnt/β-catenin-mediated tranion through tankyrase1/2 inhibition, regulates axin levels and does not affect CRE, NF-κB or TGF-β.

CIL56(CA3) has potent inhibitory effects on YAP1/Tead tranional activity and primarily targets YAP1 high and therapy-resistant esophageal adenocarcinoma cells endowed with CSC properties.

KY02111 promotes differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, may act downstream of APC and GSK3β.

Wnt agonist 1 HCl is the hydrochloride salt of Wnt agonist 1, which is a cell permeable Wnt signaling pathway activator.

SKL2001 is a novel agonist of the Wnt/β-catenin pathway.

IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation, Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells and prevents PP2A/Nkd interaction.

LGK-974 is a potent and specific PORCN inhibitor, and inhibits Wnt signaling with IC50 of 0.4 nM in TM3 cells.

Vismodegib is an orally bioavailable small molecule with potential antineoplastic activity.