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Image Product # Product Name Description Operation
  • DNA Ligase from T4-infected Escherichia coli
    TS3455

    Carboxyfluorescein succinimidyl ester (CFSE) is a fluorescent cell staining dye. CFSE is cell permeable and covalently couples, via its succinimidyl group, to intracellular molecules, notably, to intracellular lysine residues and other amine sources.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3461

    SHP099 is a highly potent, selective and orally bioavailable small-molecule SHP2 inhibitor with an IC50?value of?0.071?μM and shows no activity against SHP1.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3466

    Fatostatin is an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3467

    MKC3946 is a potent and soluble IRE1α endoribonuclease domain inhibitor which triggered modest growth inhibition in multiple myeloma cell lines, without toxicity in normal mononuclear cells.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3474

    HA15 is a molecule that targets specifically BiP/GRP78/HSPA5. HA15 displays anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3506

    LM10 is a selective tryptophan 2,3-dioxygenase (TDO) inhibitor with IC50 values of 0.62 and 2 μM for human and mouse TDO, respectively.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3514

    LXR-623 is a novel liver X-receptor(LXR) agonist with IC50 values of 179 nM and 24 nM for LXR-α and LXR-β, respectively. It is orally bioavailable and readily passes the blood-brain barrier.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3526

    R-IMPP is an inhibitor of PCSK9 secretion, half maximal inhibitory concentration [IC50] = 4.8 μM.  

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