Sildenafil is a Phosphodiesterase 5 Inhibitor with IC50 of 5.22 nM.
Dexpanthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent.
Vitamin K1 a fat-soluble, naturally occurring vitamin with antihemorrhagic and prothrombogenic activity.
Etretinate is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells.
Palmitoylethanolamide(PEA) is an endogenous fatty acid amide and selectively activates PPAR-α in vitro with an EC50 value of 3.1±0.4 μM.
Esculetin is a coumarin derivative found in various natural plant products with various biological and pharmaceutical properties including anti-edema, anti-inflammatory and anti-tumour effects. It inhibits lipoxygenases (LOs).
Isatin is an endogenous MAO inhibitor with an IC50 of 15 μM and more active against MAO-B than MAO-A.
Benzenesulfonamide ia an inhibitor of carbonic anhydrases.