Calcifediol is the major circulating metabolite of VITAMIN D3.
NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor。
Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS.
Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.
Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.
Acitretin is an orally-active metabolite of the synthetic aromatic retinoic acid agent etretinate with potential antineoplastic, chemopreventive, anti-psoratic, and embryotoxic properties.
GW4064 is an agonist of farnesoid X receptor (FXR).
Varespladib (LY315920) is a potent and selective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor with IC50 of 7 nM.