Product Name

NLG919

General description

NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor。

Synonym

1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol; Navoximod

Purity

≥98.0%(HPLC)

CAS Number

1402836-58-1

Formula

C¹⁸H²²N²O

Molecular Weight

282.38

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25℃)

DMSO

≥10mg/mL(warmed)

Ethanol

≥25mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol  Actions

NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM in cell-free assays.

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov