Docetaxel is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis.
Cabazitaxel is a Microtubule Inhibitor.
Pracinostat is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in clinical trials, allowing oral dosing.
4'-Demethylepipodophyllotoxin is an antimitotic agent which binds to monomeric tubulin, preventing micro-tubule polymerization.
Griseofulvin is an antifungal agent.
Triclabendazole is a benzimidazole, it binds to tubulin impairing intracellular transport mechanisms and interferes with protein synthesis.
Leukadherin-1 is a small molecule agonist that enhances CD11b/CD18-dependent cell adhesion to its ligand ICAM-1(an agonist for the complement receptor 3 (CD11b/CD18)).
KRIBB11, an inhibitor of the tranion factor Heat Shock Factor 1 (HSF1), abolishes the heat shock-induced luciferase activity with an IC50 of 1.2 μM.