l General Information |
Product Name | KRIBB11 |
General description | KRIBB11, an inhibitor of the transcription factor Heat Shock Factor 1 (HSF1), abolishes the heat shock-induced luciferase activity with an IC50 of 1.2 μM. |
Synonym | 2-N-(1H-indazol-5-yl)-6-N-methyl-3-nitropyridine-2,6-diamine |
Purity | ≥99.0%(HPLC) | CAS Number | 342639-96-7 |
Formula | C13H12N6O2 | Molecular Weight | 284.27 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Yellow or khaki solid |
Solubility(25℃) | DMSO | Slightly soluble |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | KRIBB11 is an inhibitor of the transcription factor Heat Shock Factor 1 (HSF1). It abolishes the heat shock-induced luciferase activity (IC50 = 1.2 μM). |
l Packaging & Storage |
Packaging | 5mg; 10mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
