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Image Product # Product Name Description Operation
  • DNA Ligase from T4-infected Escherichia coli
    TS1088

    PNU-120596 is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.

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  • DNA Ligase from T4-infected Escherichia coli
    TS1097

    5-hydroxymethyl tolterodine (PNU 200577) is a new muscarinic receptor antagonist with Kb of 0.84 nM.

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  • DNA Ligase from T4-infected Escherichia coli
    TS1100

    WAY-100635 Maleate is a potent and selective 5-HT receptor antagonist with IC50 of 0.95 nM.

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  • DNA Ligase from T4-infected Escherichia coli
    TS1108

    BRL-15572 is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor.  

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  • DNA Ligase from T4-infected Escherichia coli
    TS1115

    ADX47273 is a potent and specific mGlu5 positive allosteric modulator(PAM) with EC50 of 0.17 μM, showing no activity at other mGlu subtypes.

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  • DNA Ligase from T4-infected Escherichia coli
    TS1116

    BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3.

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  • DNA Ligase from T4-infected Escherichia coli
    TS1121

    RS-127445 is a selective 5-HT2B receptor antagonist with pKi of 9.5 and pIC50 of 10.4, exhibits >1000-fold selectivity against other 5-HT receptors.

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  • DNA Ligase from T4-infected Escherichia coli
    TS1127

    JTC-801 is a selective opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM, weakly inhibits receptors δ, κ, and μ.

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