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Image Product # Product Name Description Operation
  • DNA Ligase from T4-infected Escherichia coli
    TS3327

    A-196 is a potent and selective inhibitor of SUV420H1 and SUV420H2 with IC50 values of 0.025 and 0.144 μM, respectively more than 100-fold selective over other histone methyltransferases and non-epigenetic targets.  

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  • DNA Ligase from T4-infected Escherichia coli
    TS3335

    BIX01294 is an inhibitor of G9a histone methyltransferase with IC50 of 2.7 μM in a cell-free assay, reduces H3K9me2 of bulk histones, also weakly inhibits GLP (primarily H3K9me3), no significant activity observed at other histone methyltransferases.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3364

    Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3365

    UNC0638 is a potent, selective and cell-penetrant chemical probe for G9a and GLP with IC50 of <15 nM and 19 nM, respectively, shows selectivity over a wide range of epigenetic and non-epigenetic targets.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3379

    GSK591 (EPZ015866,GSK3203591) is a potent selective inhibitor of the arginine methyltransferase PRMT5 with IC50 of 4 nM.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3380

    MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8, respectively.  

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    • TS3380-2MG
      In-stock
      130
      - +
      TS3380-5MG
      In-stock
      170
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      TS3380-10MG
      In-stock
      300
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      TS3380-25MG
      In-stock
      560
      - +
  • DNA Ligase from T4-infected Escherichia coli
    TS3381

    BI-9564 is a selective inhibitor of BRD9 and BRD7 bromodomains with the IC50 of 75 nM and 3.4 nM, respectively.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3399

    MS049 is a potent and selective inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM, respectively.

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