Imidapril HCl is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.

Mestranol is the 3-methyl ether of ethinyl estradiol, which is a potent estrogen receptor agonist and used as oral contraceptives.

Bazedoxifene HCl is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of  23 nM and 89 nM, respectively.

GSK1292263 is a novel GPR119 agonist, showing potential for the treatment of type 2 diabetes.

Bazedoxifene Acetate is a third generation selective estrogen receptor modulator (SERM).

Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM.

Equol ,a metabolite of soybeans, is an important isoflavone in humans，specifically binds to 5α-DHT, has a modest affinity for recombinant estrogen receptor Erβ.

Hexestrol binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.