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Image Product # Product Name Description Operation
  • DNA Ligase from T4-infected Escherichia coli
    TS3236

    FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of  14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3251

    Cyclo (-RGDfK) is a potent and selective αvβ3 integrin inhibitor.  

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  • DNA Ligase from T4-infected Escherichia coli
    TS3255

    Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.  

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  • DNA Ligase from T4-infected Escherichia coli
    TS3296

    Ixabepilone is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3352

    PU-H71 is a potent and selective inhibitor of HSP90 with IC50 of 51 nM.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3354

    Dynasore is a cell-permeable, reversible non-competitive dynamin inhibitor of GTPase activity of dynamin 1/2, with IC50 of 15 μM in a cell-free assay, also inhibits the mitochondrial dynamin Drp1, with no effect against other small GTPase.

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  • DNA Ligase from T4-infected Escherichia coli
    TS3407

    Cucurbitacin B, an oxygenated tetracyclic triterpenoid compound extracted from Cucurbitaceae plant species, is a long-term anticancer agent by disruption of microtubule polymerization.  

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  • DNA Ligase from T4-infected Escherichia coli
    TS3435

    BAY 1217389 is an orally bioavailable, selective inhibitor of the serine/threonine kinase monopolar spindle 1 (Mps1) with IC50 values below 10 nmol/L while showing an excellent selectivity profile.

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