Product Name

Nootkatone      

General description

(+)-Nootkatone  has antiallergic, anti-inflammatory, and antiplatelet activities.

Synonym

(4R,4aS,6R)-4,4a-dimethyl-6-prop-1-en-2-yl-3,4,5,6,7,8-hexahydronaphthalen-2-one

Purity

≥98.0%(GC)

CAS Number

4674-50-4

Formula

C¹⁵H²²O

Molecular Weight

218.33458

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Pale Yellow Solid

l  Biological Information

Biochem/Physiol  Actions

Nootkatone has antiproliferative activity.Plant-derived acaricides nootkatone and carvacrol can suppress Ixodes scapularis Say and Amblyomma americanum (L.) (Acari: Ixodidae).(+)-Nootkatone has potent inhibitory effect on collagen-, thrombin-, and AA-induced platelet aggregation, it also has a significant inhibitory effect on rat platelet aggregation ex vivo. Nootkatone, a naturally occurring AMPK activator, can stimulate energy metabolism and prevents diet-induced obesity by activating AMPK.Nootkatone is a strong repellent and toxicant to Formosan subterranean termites, the lowest effective concentration tested is 10 micrograms/g substrate.

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov