l General Information |
Product Name | Bevirimat |
General description | Bevirimat is an anti-HIV drug derived from a betulinic acid-like compound. |
Synonym | YK FH312; FH11327; MPC-4326 |
Purity | ≥98.0%(HPLC) | CAS Number | 174022-42-5 |
Formula | C36H56O6 | Molecular Weight | 584.82624 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to Beige Solid |
Solubility(25°C) | DMSO | ≥50mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Bevirimat is a drug derived from a betulinic acid-like compound, first isolated from the Chinese herb Syzygium claviflorum, with activity against human immunodeficiency virus (HIV). Bevirimat acts by binding to the Gag capsid precursor protein and blocking its conversion to mature capsid protein by protease cleavage. It potently inhibits replication in both wild-type and drug-resistant (reverse transciptase or protease) HIV-1 isolates. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
