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Home > Products > Small molecule > Protein Tyrosine Kinase > Lazertinib (YH25448,GNS-1480)

Lazertinib (YH25448,GNS-1480)

Product #: TS3644
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Details

l  General Information

Product Name

Lazertinib

General description

Lazertinib is a potent, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively, showing much higher IC50 values aganist ErbB2 and ErbB4.

Synonym

YH25448,GNS-1480

Purity

≥98.5%(HPLC)

CAS Number

1903008-80-9

Formula

C30H34N8O3

Molecular Weight

554.64276

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

Slightly soluble

Ethanol

Insoluble

Water

Very slightly soluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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