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BTSA1

Product #: TS3619
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Details

l  General Information

Product Name

BTSA1

General description

BTSA1 is a pharmacologically optimized BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. It effectively promotes  apoptosis in leukemia cell lines and patient samples while sparing healthy cells.

Synonym

5-phenyl-2-(4-phenyl-1,3-thiazol-2-yl)-4-(1,3-thiazol-2-yldiazenyl)-1~{H}-pyrazol-3-one

Purity

≥98.5%(HPLC)

CAS Number

314761-14-30

Formula

C21H14N6OS2

Molecular Weight

430.51

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Red to Dark Red-Brown Solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

Insoluble

Water

Very slightly soluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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