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GSK'963

Product #: TS3614
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Details

l  General Information

Product Name

GSK'963

General description

GSK'963 is a chiral small-molecule inhibitor of RIP1 kinase with an IC50 of 29 nM in FP binding assays. It is >10 000-fold selective for RIP1 over 339 other kinases.

Synonym

GTPL10132; 2,2-dimethyl-1-[(3~{S})-3-phenyl-3,4-dihydropyrazol-2-yl]propan-1-one

Purity

≥98.5%(HPLC)

CAS Number

2049868-46-2

Formula

C14H18N2O

Molecular Weight

230.31

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Beige Solid

Solubility(25°C)

DMSO

≥35mg/mL

Ethanol

≥35mg/mL

Water

Very slightly soluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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