l General Information |
Product Name | Autophinib |
General description | Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay and rapamycin induced autophagy assay. The IC50 value for Vps34 is 19 nM in vitro. |
Synonym | 6-chloro-~{N}-(5-methyl-1~{H}-pyrazol-3-yl)-2-(4-nitrophenoxy)pyrimidin-4-amine |
Purity | ≥98.5%(HPLC) | CAS Number | 1644443-47-9 |
Formula | C14H11ClN6O3 | Molecular Weight | 346.73 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥50mg/mL |
Ethanol | Insoluble |
Water | Very slightly soluble |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
