l General Information |
Product Name | GSK180736A |
General description | GSK180736A, developed as a Rho-associated, coiled-coil-containing protein kinase inhibitor, binds to GRK2(G protein-coupled receptor kinase 2) with logIC50 pf -6.6 (logIC50 -4.0 for GRK5 and >-3 for GRK1) ≥400-fold selective for GRK2 over both GRK1 and GRK5. |
Synonym | HMS3305J10; GSK180736 |
Purity | ≥98.5%(HPLC) | CAS Number | 817194-38-0 |
Formula | C19H16FN5O2 | Molecular Weight | 365.36 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to Beige Solid |
Solubility(25°C) | DMSO | ≥50mg/mL |
Ethanol | Slightly soluble |
Water | Very slightly soluble |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
