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GSK'872 (GSK2399872A)

Product #: TS3544
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Details

l  General Information

Product Name

GSK'872 (GSK2399872A)

General description

GSK'872 (GSK2399872A) is a potent and selective RIP3 kinase inhibitor which binds RIP3 kinase domain with high affinity (IC50=1.8 nM) and inhibits kinase activity with IC50 of 1.3 nM. It has minimal cross-reactivity. 

Synonym

GSK872; GSK(Acute)872; AOB4887; EX-A1400

Purity

≥98.5%(HPLC)

CAS Number

1346546-69-7

Formula

C19H17N3O2S2

Molecular Weight

383.49

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

Insoluble

Water

Very slightly soluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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