Product Name

PF-06273340

General description

PF-06273340 is a highly potent, kinases elective, well-tolerated pan-Trk inhibitor with IC50 values of 6, 4, 3 nM for TrkA, TrkB, Trk C, respectively. 

Synonym

I136775ABW

Purity

≥98.5%(HPLC)

CAS Number

1402438-74-7

Formula

C²³H²²ClN⁷O³

Molecular Weight

479.92

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Yellow to Brown Solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

Slightly soluble

Water

Very slightly soluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov