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MSC2530818

Product #: TS3512
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l  General Information

Product Name

MSC2530818

General description

MSC2530818, a CDK8 inhibitor with the IC50 of 2.6 nM, displays excellent kinase selectivity, biochemical and cellular potency, microsomal stability, and is orally bioavailable.

Synonym

[(2~{S})-2-(4-chlorophenyl)pyrrolidin-1-yl]-(3-methyl-2~{H}-pyrazolo[3,4-b]pyridin-5-yl)methanone

Purity

≥98.5%(HPLC)

CAS Number

1883423-59-3

Formula

C18H17ClN4O

Molecular Weight

340.81

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

≥50mg/mL

Water

Very slightly soluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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