l  General Information  | 
Product Name  | MSC2530818  | 
General description  | MSC2530818, a CDK8 inhibitor with the IC50 of 2.6 nM, displays excellent kinase selectivity, biochemical and cellular potency, microsomal stability, and is orally bioavailable.  | 
Synonym  | [(2~{S})-2-(4-chlorophenyl)pyrrolidin-1-yl]-(3-methyl-2~{H}-pyrazolo[3,4-b]pyridin-5-yl)methanone  | 
Purity  | ≥98.5%(HPLC)  | CAS Number  | 1883423-59-3  | 
Formula  | C18H17ClN4O  | Molecular Weight  | 340.81  | 
Suitability  | BioReagent, suitable for cell culture, etc.  | 
l  Physical and Chemical Information  | 
Appearance  | Solid  | 
Solubility(25°C)  | DMSO  | ≥50mg/mL  | 
Ethanol  | ≥50mg/mL  | 
Water  | Very slightly soluble  | 
l  Storage  | 
Storage temp.  | -20°C  | 
l  Precautions and Disclaimer  | 
This product is for R&D use only, not for drug, household, or other uses.  | 
l  References  | 
1.    http://www.drugbank.ca 2.    https://ncit.nci.nih.gov 3.    https://www.ncbi.nlm.nih.gov  |