l General Information |
Product Name | APS-2-79 HCl |
General description | APS-2-79 HCl is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK. IC50=120 ± 23 nM. |
Synonym | 6,7-dimethoxy-~{N}-(2-methyl-4-phenoxyphenyl)quinazolin-4-amine; hydrochloride |
Purity | ≥98.5%(HPLC) | CAS Number | 2002381-31-7 |
Formula | C23H22ClN3O3 | Molecular Weight | 423.89 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥50mg/mL |
Ethanol | ≥50mg/mL |
Water | Insoluble |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
