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Kobe0065

Product #: TS3476
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Details

l  General Information

Product Name

Kobe0065

General description

Kobe0065 is H-Ras-cRaf1 interaction inhibitor, exhibiting potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.

Synonym

1-(3-chloro-4-methylphenyl)-3-[2,6-dinitro-4-(trifluoromethyl)anilino]thiourea 

Purity

≥98.5%(HPLC)

CAS Number

436133-68-5

Formula

C15H11ClF3N5O4S

Molecular Weight

449.79

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Beige Solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

≥5mg/mL

Water

Very slightly soluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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