l  General Information  | 
Product Name  | Kobe0065  | 
General description  | Kobe0065 is H-Ras-cRaf1 interaction inhibitor, exhibiting potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.  | 
Synonym  | 1-(3-chloro-4-methylphenyl)-3-[2,6-dinitro-4-(trifluoromethyl)anilino]thiourea    | 
Purity  | ≥98.5%(HPLC)  | CAS Number  | 436133-68-5  | 
Formula  | C15H11ClF3N5O4S  | Molecular Weight  | 449.79  | 
Suitability  | BioReagent, suitable for cell culture, etc.  | 
l  Physical and Chemical Information  | 
Appearance  | White to Beige Solid  | 
Solubility(25°C)  | DMSO  | ≥50mg/mL  | 
Ethanol  | ≥5mg/mL  | 
Water  | Very slightly soluble  | 
l  Storage  | 
Storage temp.  | -20°C  | 
l  Precautions and Disclaimer  | 
This product is for R&D use only, not for drug, household, or other uses.  | 
l  References  | 
1.    http://www.drugbank.ca 2.    https://ncit.nci.nih.gov 3.    https://www.ncbi.nlm.nih.gov  |