l  General Information  | 
Product Name  | CCT245737  | 
General description  | CCT245737 is an orally active CHK1 inhibitor with The IC50 of 1.4 nM. It exhibits >1,000-fold selectivity against CHK2 and CDK1.  | 
Synonym  | SRA737; 5-[[4-[[(2R)-morpholin-2-yl]methylamino]-5-(trifluoromethyl)pyridin-2-yl]amino]pyrazine-2-carbonitrile    | 
Purity  | ≥98.5%(HPLC)  | CAS Number  | 1489389-18-5  | 
Formula  | C16H16F3N7O  | Molecular Weight  | 379.34  | 
Suitability  | BioReagent, suitable for cell culture, etc.  | 
l  Physical and Chemical Information  | 
Appearance  | Solid  | 
Solubility(25°C)  | DMSO  | ≥50mg/mL  | 
Ethanol  | ~5mg/mL  | 
Water  | Very slightly soluble  | 
l  Storage  | 
Storage temp.  | -20°C  | 
l  Precautions and Disclaimer  | 
This product is for R&D use only, not for drug, household, or other uses.  | 
l  References  | 
1.    http://www.drugbank.ca 2.    https://ncit.nci.nih.gov 3.    https://www.ncbi.nlm.nih.gov  |