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HPI-4 (Ciliobrevin A)

Product #: TS3449
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l  General Information

Product Name

HPI-4

General description

HPI-4 is a hedgehog (Hh) pathway antagonist. It blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo.

Synonym

Hedgehog Pathway Inhibitor 4; Ciliobrevin A

Purity

≥98.5%(HPLC)

CAS Number

302803-72-1

Formula

C17H9Cl2N3O2

Molecular Weight

358.18

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Off-White to Orange Solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

Slightly soluble

Water

Very slightly soluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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