l General Information |
Product Name | RK-33 |
General description | RK-33 is a first-in-class small molecule inhibitor of DDX3 (a RNA helicase) and causes G1 cell cycle arrest, induces apoptosis, and promotes radiation sensitization in DDX3-overexpressing cells. |
Synonym | 3,7-bis[(4-methoxyphenyl)methyl]diimidazo[4,3-a:5',4'-d][1,3]diazepin-8-one |
Purity | ≥98.5%(HPLC) | CAS Number | 1070773-09-9 |
Formula | C23H20N6O3 | Molecular Weight | 428.44 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25°C) | DMSO | ≥50mg/mL |
Ethanol | Insoluble |
Water | Very slightly soluble |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |