l  General Information  | 
Product Name  | RK-33  | 
General description  | RK-33 is a first-in-class small molecule inhibitor of DDX3 (a RNA helicase) and causes G1 cell cycle arrest, induces apoptosis, and promotes radiation sensitization in DDX3-overexpressing cells.  | 
Synonym  | 3,7-bis[(4-methoxyphenyl)methyl]diimidazo[4,3-a:5',4'-d][1,3]diazepin-8-one    | 
Purity  | ≥98.5%(HPLC)  | CAS Number  | 1070773-09-9  | 
Formula  | C23H20N6O3  | Molecular Weight  | 428.44  | 
Suitability  | BioReagent, suitable for cell culture, etc.  | 
l  Physical and Chemical Information  | 
Appearance  | Solid  | 
Solubility(25°C)  | DMSO  | ≥50mg/mL  | 
Ethanol  | Insoluble  | 
Water  | Very slightly soluble  | 
l  Storage  | 
Storage temp.  | -20°C  | 
l  Precautions and Disclaimer  | 
This product is for R&D use only, not for drug, household, or other uses.  | 
l  References  | 
1.    http://www.drugbank.ca 2.    https://ncit.nci.nih.gov 3.    https://www.ncbi.nlm.nih.gov  |