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RK-33

Product #: TS3448
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Details

l  General Information

Product Name

RK-33

General description

RK-33 is a first-in-class small molecule inhibitor of DDX3 (a RNA helicase) and causes G1 cell cycle arrest, induces apoptosis, and promotes radiation sensitization in DDX3-overexpressing cells.

Synonym

3,7-bis[(4-methoxyphenyl)methyl]diimidazo[4,3-a:5',4'-d][1,3]diazepin-8-one 

Purity

≥98.5%(HPLC)

CAS Number

1070773-09-9

Formula

C23H20N6O3

Molecular Weight

428.44

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Solid

Solubility(25°C)

DMSO

≥50mg/mL

Ethanol

Insoluble

Water

Very slightly soluble

l  Storage

Storage temp.

-20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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